BIOSSANCE

BIOSSANCE

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Your healthiest skin, our healthiest planet
🔬 Clinically effective skincare with results
🌱 Sugarcane-derived squalane

In 2003, our scientists began a project that would change the world. From inside our Berkeley labs, they developed patented technology that allowed us to create an accessible cure for malaria. Today, over 120 million royalty-free treatments have been successfully given thanks to this technology. Inspired to continue using innovative biotechnology to make a positive impact on the world, we turned t

07/12/2026

Why do we go to such lengths to encapsulate our probiotics? Because your skin's microbiome is a living ecosystem and it needs live, active support to stay balanced.

Our advanced encapsulation technology keeps our live probiotics protected in natural alginate polymers, ensuring they stay fresh and potent until the very moment they touch your skin.

Once activated, they deliver a precise burst of calming, balancing power to quiet reactivity, reduce redness, and soothe skin that feels overwhelmed.

Same formula you love. New, improved pump for the perfect application every time. Now $49 (was $54).

Follow + comment PROBIOTIC and we'll send you the link.

07/10/2026

When reactive skin finally meets its match. 🌊

had been searching for a moisturizer that could actually keep up with her skin, without triggering acne flares, irritation, or that dreaded greasy finish. She found it in our Squalane + Probiotic Gel Moisturizer, and it only took three days to notice a difference.

Here's why her skin responded so well:

🌿 Sugarcane-derived squalane: a bioidentical match for your skin's natural lipids, it replenishes moisture at the barrier level without ever clogging pores
🌿 Encapsulated live probiotics: delivered intact to restore microbiome balance and calm reactive, sensitive skin from within
🌿 Weightless gel texture: absorbs instantly for all-day hydration with zero greasiness

Science that works with your skin, not against it.

Find the Squalane + Probiotic Gel Moisturizer at Sephora, link in bio.

Photos from BIOSSANCE's post 07/09/2026

The proof is skin-deep

100% agreed skin felt immediately more comforted, calmer, and less irritated. 88% saw immediate improvement in redness. 100% said excess oil felt more balanced with visibly tighter-looking pores in one week.

Recognized by the National Eczema Association and the National Rosacea Society. Dermatologist and pediatrician tested. Microbiome-friendly, and gentle enough for sensitive skin.

Real results, the kind your skin can trust.
Follow + comment PROBIOTIC and we'll send you the link.

07/09/2026

Same formula your skin loves. A better everything else.

A mess-free pump that dispenses cleanly every time, so application is effortless and hygienic for reactive skin. A recyclable glass bottle that keeps the formula fresh and is easier to recycle when you’re done. A more modern look, and a lower price to match.

The relief didn’t change. The experience did.

Follow + comment PROBIOTIC and we’ll send you the link.

07/08/2026

Same formula your skin loves. A better everything else.

A mess-free pump that dispenses cleanly every time, so application is effortless and hygienic for reactive skin. A recyclable glass bottle that keeps the formula fresh and is easier to recycle when you're done. A more modern look, and a lower price to match.

The relief didn't change. The experience did.

Follow + comment PROBIOTIC and we'll send you the link.

07/07/2026

Quiet the chaos. Our Squalane + Probiotic Gel Moisturizer just got a redesign and it's now available at Sephora.

Stubborn redness. Lingering irritation. Unexpected breakouts. When your skin feels like it's acting out, it's time for a reset.

The solution 5,000+ of you love to restore harmony is back, better than ever. We've redesigned it with a new airtight pump to protect our potent, encapsulated probiotic technology, ensuring a fresh, concentrated dose of relief in every press.

The result? Instantly soothed, clearer-looking skin with balanced oil and deep, weightless hydration.

Follow + comment PROBIOTIC and we'll send you the link!

07/05/2026

Instant relief from skin's loudest moments. Redness, irritation, flare-ups — your skin deserves a solution that actually speaks to what it needs. We've taken the Squalane + Probiotic Gel Moisturizer you already know and trust, and reimagined how it reaches your skin.

Meet our new airtight pump. Designed for a more seamless, precise application, it ensures you get the full benefit of our powerful, encapsulated probiotics in every single press.

Why the upgrade? Because 100% of our clinical trial participants saw calmer, comforted skin after just one use. It's the same potent, skin-harmonizing formula that earned 5,000+ five-star reviews, now in an elevated design that makes achieving that calm easier than ever.

Preview it on the Sephora app 7.6. Available at Sephora.com on 7.7.
Comment CALM and we'll send you the direct link to sign up.

07/02/2026

We brought our two firming heroes together for the first time. Meet the Firm & Restore Set.

The Squalane + Firm and Lift Dual Serum and Growth Factor Firming Moisturizer are now available together, each perfectly sized for a month of use. If either has been on your radar, this is your moment.

Two steps powered by biomimetic growth factors and cyclic peptides that work with your skin to visibly lift, firm, and restore bounce. Clinically proven firmness in 4 weeks.

Shop the Firm and Restore Set on the Sephora App July 3 and at Sephora, Sephora at Kohl's, and Sephora Canada July 4. Comment FIRM below and we'll send you the link. 🔗

07/01/2026

Summer vacation is almost here, and we are making sure our skin is ready for it. ☀️

Our Annual Summer Stock Up Event is the perfect time to grab the hydrators and glow-getters that hold up in the heat, travel beautifully, and deliver all season long. 30% off summer essentials, now through the link in bio.

06/30/2026

Your summer skin routine starts here.

Heat, sweat, sunscreen. Summer puts your skin through a lot. Our Squalane + Amino Aloe Gentle Cleanser is formulated to clear it all out gently, with an amino acid complex that lifts daily buildup without disrupting your barrier. Sugarcane-derived squalane replenishes moisture as you cleanse, so you end every wash feeling clean, not stripped.

Find it at Sephora in stores and online. Link in bio.

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San Francisco, CA