Optometry Insight By Abubakar

Adenoviral Keratoconjunctivitis Leads to Persistent Ocular Surface Damage

Up to 18 months following infection, patients demonstrated substantial goblet cell loss, squamous metaplasia and measurable tear film instability, likely contributing to dry eye symptoms.

According to the study authors, these findings have several clinical implications: “First, patients recovering from AKC should be counseled about the potential for long-term dry eye symptoms and the need for continued follow-up. Second, early and aggressive anti-inflammatory treatment during the acute phase might potentially reduce the degree of goblet cell loss and subsequent dry eye development, although this hypothesis requires further investigation.” Lastly, they wrote, “long-term management strategies, including artificial tears, antiinflammatory agents and mucin secretagogues, may be necessary in patients with persistent symptoms.”

Read more: https://www.reviewofoptometry.com/article/adenoviral-keratoconjunctivitis-leads-to-persistent-ocular-surface-damage